Fig 6. Changes in CD8+ T cell populations in animals infected with NiV.

Linear regression analysis of the percent of CD8^dim (A, B) and CD8^bright (C, D) T cells within the CD3+ cell population of individual animals are shown for both the low (A, C) and high (B, D) dose groups over the course of disease. The r-values for the linear regression analyses are provided in S1 Table. Linear regression analysis was performed on samples from all animals through day 12 (acute phase) with additional analysis of the surviving animal over the entire course of disease (blue dashed line). Panels E and F show the populations of CD8^dim and CD8^bright T cells, respectively where red circles indicate the low dose group and blue squares indicate the high dose group.