Table 1.

Visit schedule and assessments

Procedures	Visits
	Screening	Baseline	Intervention	Week 4 post-intervention (only second stage of study)	Month 6 after baseline (first stage of study) or intervention (second stage of study)	Y1	Y2	Y3	Y5
Demographics		X
Medical history		X
Physical examination		X		X
Consent		X	X
Blood test		X		X	X	X	X	X	X
Imaging	X				X	X	X	X	X
Questionnaire		X		X	X	X	X	X	X
Cryoablation or partial nephrectomy			X
Case report form		X	X	X	X	X	X	X	X
Adverse event reporting		X	X	X	X	X	X	X	X
Biobanking of blood/urine/tissue		X	X	X	X	X	X	X	X