Table 1.
Basic characteristics of the study population with or without incident cancer
| Non-gastric cancer | Incident gastric cancer | P value | Non-colorectal cancer | Incident colorectal cancer | P value | |
| Number | 15 878 | 48 | 15 874 | 52 | ||
| Male, % (N) | 53.9 (8553) | 66.7 (32) | 0.084 | 53.8 (8547) | 73.1 (38) | 0.006 |
| Exerciser, % (N) | 17.2 (2721) | 18.8 (9) | 0.70 | 17.2 (2722) | 15.7 (8) | 1.00 |
| Never smoker, % (N) | 59.5 (9419) | 37.5 (18) | 0.007 | 59.5 (9414) | 44.2 (23) | 0.08 |
| Ex smoker, % (N) | 18.8 (2979) | 27.1 (13) | 18.8 (2978) | 26.9 (14) | ||
| Current smoker, % (N) | 21.7 (3440) | 35.4 (17) | 21.7 (3442) | 28.8 (15) | ||
| Diabetes, % (N) | 1.9 (295) | 8.3 (4) | 0.012 | 1.9 (297) | 3.8 (2) | 0.26 |
| Alcohol consumption, mg/week | 32.5 (49.3) | 38.5 (51.3) | 0.41 | 32.4 (49.2) | 54.9 (54.9) | 0.002 |
| Age, year | 43.8 (9) | 52.2 (8.3) | <0.001 | 43.8 (9) | 45.3 (7.4) | 0.23 |
| BMI, kg/m2 | 22.3 (3.2) | 23 (3.5) | 0.10 | 22.3 (3.2) | 24.2 (3.8) | <0.001 |
| Systolic blood pressure, mm Hg | 114.7 (15.2) | 118 (15.8) | 0.13 | 114.7 (15.2) | 117.1 (13.4) | 0.25 |
| Diastolic blood pressure, mm Hg | 71.7 (10.5) | 73.7 (10) | 0.19 | 71.7 (10.5) | 74.4 (9.1) | 0.065 |
| AST, IU/L | 18.1 (9.4) | 18.5 (5.1) | 0.75 | 18.1 (9.4) | 17.8 (5.7) | 0.83 |
| ALT, IU/L | 20.7 (15.2) | 22.7 (11.3) | 0.35 | 20.7 (15.2) | 24.2 (12.5) | 0.097 |
| GGT, IU/L | 19.9 (17.5) | 21.4 (16.3) | 0.57 | 19.9 (17.5) | 20.5 (12.8) | 0.81 |
| Alb, g/dL | 4.33 (0.2) | 4.31 (0.18) | 0.53 | 4.33 (0.2) | 4.29 (0.29) | 0.13 |
| Platelet, 103/mL | 24.4 (5.6) | 24.9 (6.1) | 0.49 | 24.4 (5.6) | 25.3 (5.2) | 0.27 |
| FIB4 index | 0.79 (0.38) | 0.89 (0.33) | 0.057 | 0.79 (0.38) | 0.7 (0.25) | 0.11 |
| NAFLD fibrosis score | 1.07 (0.26) | 1.1 (0.31) | 0.34 | 1.07 (0.26) | 1.08 (0.27) | 0.78 |
| Total cholesterol, mg/dL | 200.8 (34.2) | 217.6 (32.1) | 0.001 | 200.8 (34.2) | 213.4 (31.4) | 0.009 |
| Triglycerides, mg/dL | 84 (64.7) | 114.2 (57.3) | 0.001 | 84 (64.5) | 123.1 (108.3) | 0.012 |
| LDL cholesterol, mg/dL | 128 (31.3) | 145 (30.5) | <0.001 | 128 (31.3) | 140.4 (34.8) | 0.004 |
| HDL cholesterol, mg/dL | 55.9 (15.3) | 49.7 (12.8) | 0.002 | 55.9 (15.3) | 51.3 (16.8) | 0.029 |
| Uric acid, mg/dL | 4.81 (1.34) | 5.27 (1.53) | 0.018 | 4.81 (1.34) | 5.62 (1.44) | <0.001 |
| Fasting blood glucose, mg/dL | 95.4 (13.2) | 101.1 (18) | 0.032 | 95.4 (13.2) | 97.4 (11.8) | 0.26 |
| HbA1c, % | 5.2 (0.49) | 5.26 (0.69) | 0.54 | 5.2 (0.49) | 5.2 (0.45) | 0.96 |
χ2 test is applied to categorical variables and t test is applied to continuous variables. Categorical variables are expressed as percentages (n). Continuous variables are expressed as the means (SD).
ALT, alanineaminotransferase; AST, aspartateaminotransferase; Alb, albumin; FIB4, fibrosis-4index; GGT, gamma-glutamyltransferase; HDL, high-density lipoprotein; HbA1c, hemoglobinA1c; LDL, low-density lipoprotein; NAFLD, non-alcoholic fatty liver disease.