Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Quantitative application of TI-SAMDI-MS. (a) Spectra showing before and after CYP2C9 enzyme reaction of tolbutamide to hydroxy-tolbutamide by hydroxylation. (b) Plot showing product yield concentration of hydroxy-tolbutamide to reaction times for calculation of velocity for enzyme kinetics. (c) Michaelis–Menten kinetic plot of reaction as determined by TI-SAMDI-MS.
