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. 2019 Jun 12;12:4509–4516. doi: 10.2147/OTT.S205169

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© 2019 Zhao et al.

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MiRNA-124 downregulated ROCK1, which upregulated UCA1. Comparing to two controls, overexpression of ROCK1 resulted in the downregulation of ROCK1 mRNA in cells of HCC cell lines SNU-398 and SNU-449 (A). In contrast, ROCK1 overexpression mediated the upregulation of UCA1 in cells of both cell lines (B) (*p<0.05).