Table 3.
Univariate and multivariate linear correlation analysis on the most frequent bacteria and disease, age, gender, and survival patients
| Linear correlation analysis | Univariate analysis | Multivariate analysis |
|---|---|---|
| Parameters | R (p-value) | Rpartial; p-value |
| Multiple linear correlation coefficient =1.0 | ||
| Survival patients/PHC | −0.45 (<0.0001) * | Rpartial= −0.99; p-value <0.0001 * |
| Survival patients/CCA | −0.22 (0.0062) * | Rpartial = −0.98; p-value <0.0001 * |
| Survival patients/ACA | 0.33 (<0.0001) * | Rpartial = −0.90; p-value <0.0001 * |
| Survival patients/GBC | −0.55 (<0.0001) * | Rpartial = −0.98; p-value <0.0001 * |
| Survival patients/CHL | 0.43 (<0.0001) * | Rpartial = −0.24; p-value =0.0040 * |
| Survival patients/E. coli | −0.21 (0.0088) * | Rpartial = 0.04; p-value =0.68 |
| Survival patients/K. pneumoniae | 0.16 (0.0495) * | Rpartial = 0.05; p-value =0.58 |
| Survival patients/Pseudomonas aeruginosa | 0.23 (0.0038) * | Rpartial = −0.07; p-value =0.45 |
| Survival patients/Meropenem | −0.20 (0.0157) * | Rpartial = 0.05; p-value =0.59 |
| Survival patients/Imipenem | 0.08 (0.31) | Rpartial = −0.02; p-value =0.84 |
| Survival patients/Ertapenem | −0.13 (0.11) | Rpartial = −0.08; p-value =0.38 |
| Survival patients/Age | −0.10 (0.20) | Rpartial = −0.16; p-value =0.06 |
| Survival patients/Gender | −0.09 (0.25) | Rpartial = −0.11; p-value =0.10 |
| Multiple linear correlation coefficient =0.63 | ||
| PHC/E. coli | 0.52 (<0.0001) * | Rpartial =0.29; p-value =0.0003 * |
| PHC/K. pneumoniae | −0.46 (<0.0001) * | Rpartial =−0.27; p-value =0.0008 * |
| PHC/Pseudomonas aeruginosa | 0.13 (0.12) | Rpartial =0.058; p-value =0.48 |
| Multiple linear correlation coefficient =0.59 | ||
| CCA/E. coli | −0.35 (<0.0001) * | Rpartial =−0.42; p-value <0.0001 * |
| CCA/K. pneumoniae | 0.42 (<0.0001) * | Rpartial =−0.09; p-value =0.26 |
| CCA/Pseudomonas aeruginosa | −0.36 (<0.0001) * | Rpartial =−0.43; p-value <0.0001 * |
| Multiple linear correlation coefficient =0.16 | ||
| GBC/E. coli | −0.12 (0.16) | Rpartial =0.01; p-value =0.93 |
| GBC/K. pneumoniae | 0.13 (0.11) | Rpartial =0.12; p-value =0.16 |
| GBC/Pseudomonas aeruginosa | 0.03 (0.70) | Rpartial =0.08; p-value =0.32 |
| Multiple linear correlation coefficient =0.16 | ||
| ACA/E. coli | −0.08 (0.31) | Rpartial =0.06; p-value =0.44 |
| ACA/K. pneumoniae | 0.25 (0.0017) * | Rpartial =0.20; p-value =0.0131 * |
| ACA/Pseudomonas aeruginosa | −0.12 (0.15) | Rpartial =0.04; p-value =0.65 |
| Multiple linear correlation coefficient =0.52 | ||
| CHL/E. coli | −0.21 (0.0099) * | Rpartial =−0.22; p-value =0.0083 * |
| CHL/K. pneumoniae | 0.43 (<0.0001) * | Rpartial =0.06; p-value =0.45 |
| CHL/Pseudomonas aeruginosa | −0.40 (<0.0001) * | Rpartial =−0.33; p-value <0.0001 * |
| Multiple linear correlation coefficient =0.59 | ||
| E coli/Meropenem | 0.36 (<0.0001) * | Rpartial =0.32; p-value =0.0001 * |
| E coli/Imipenem | 0.51 (<0.0001) * | Rpartial =0.49; p-value <0.0001 * |
| E coli/Ertapenem | 0.15 (0.06) | Rpartial = −0.30; p-value =0.0002 * |
| Multiple linear correlation coefficient =0.76 | ||
| K. pneumoniae/Meropenem | −0.24 (0.0027) * | Rpartial =0.10; p-value =0.24 |
| K. pneumoniae/Imipenem | −0.75 (<0.0001) * | Rpartial =−0.72; p-value <0.0001 * |
| K. pneumoniae/Ertapenem | −0.33 (<0.0001) * | Rpartial =0.02; p-value =0.65 |
| Multiple linear correlation coefficient =0.56 | ||
| Pseudomonas aeruginosa/Meropenem | 0.029 (0.72) | Rpartial =−0.35; p-value <0.0001 * |
| Pseudomonas aeruginosa/Imipenem | 0.45 (<0.0001) * | Rpartial =0.40; p-value <0.0001 * |
| Pseudomonas aeruginosa/Ertapenem | 0.35 (<0.0001) * | Rpartial =0.33; p-value <0.0001 * |
Notes: *significant test; R = Pearson’s linear correlation coefficient; Rpartial= the partial correlation coefficient is the coefficient of correlation of the variable with the dependent variable, adjusted for the effect of the other variables in the mode
Abbreviations: CCA, cholangiocarcinoma; PHC, carcinoma of the head of the pancreas; ACA, ampullary carcinoma; GBC, gallbladder carcinoma; CHL, cholelithiasis.