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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Semin Perinatol. 2019 Jan 14;43(3):123–131. doi: 10.1053/j.semperi.2019.01.001

Table 1.

DSM V diagnostic criteria for opioid use disorder.36

Two or more of the following within a 12-month period:
• Using larger amounts of opioids or over a longer period of time than was intended
• Persistent desire to cutback or unsuccessful efforts to control use
• Substantial amount of time spent obtaining, using or recovering from use
• Craving or strong desire to use opioids
• Failure to fulfill obligations at work, home or school due to use
• Continued use despite recurrent social or interpersonal problems caused or exacerbated by use
• Giving up or reducing social, occupational or recreational activities due to use
• Recurrent opioid use in situations that may be physically dangerous
• Continued use despite knowledge of having a physical or psychological problem caused or exacerbated by opioids
• Tolerance*
• Development of withdrawal syndrome if use stopped*
Opioid use disorder severity:
• Mild 2-3 symptoms or signs
• Moderate 4-5 symptoms or signs
• Severe 6 or more symptoms or signs
*

Tolerance and withdrawal criteria not met if opioids only used under medical supervision and as intended.