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. 2019 Jun 12;11:5353–5363. doi: 10.2147/CMAR.S208233

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© 2019 Lin et al.

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Biological effect of PLAU on the proliferation, migration and angiogenesis ability in HT-29 cell line. (A) The expression of PLAU in CRC tissues and normal colorectal tissues in TCGA datasets. (B) CCK-8 assay was performed to detect the viability of HT-29 cell after transfecting with PLAU plasmid or inhibitor. (C) Transwell assay performed to assess the invasion ability of HT-29 cell after transfecting with PLAU plasmid or inhibitor. (D) HUVEC were cultured on Matrigel-counted plate with CM from HT-29 cell transfecting with PLAU plasmid or inhibitor. Data were shown as mean ± SD. *P<0.05, **P<0.01, ***P<0.001.

Abbreviations: COAD, colon adenocarcinoma; HUVEC, human umbilical vein endothelial cell; CM, conditional medium.