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Lack of BDNF expression in hippocampal interneurons. A, B, Pair of photomicrographs illustrating PARV-positive interneurons (arrows in A) in the CA3 region, which are unlabeled with the BDNF riboprobe (B).C, Several CALR-positive interneurons (arrows) in the CA3 region show negative hybridization for BDNF mRNA; dashed lines label the pyramidal layer (sp). Notice the dense hybridization signals in the pyramidal layer. sr, Stratum radiatum; so, stratum oriens. Scale bar, 50 μm.
