Skip to main content
. 1996 Jul 15;16(14):4322–4334. doi: 10.1523/JNEUROSCI.16-14-04322.1996

Fig. 10.

Fig. 10.

Cannabinoid receptor activation does not affect GABA-mediated inhibitory neurotransmission. Inward IPSCs were recorded from a −70 mV holding potential with 140 mminternal Cl− as described in Materials and Methods. Win 55,212-2 (100 nm) had no effect on the amplitude of IPSCs evoked by stimulation of the presynaptic cell with an extracellular electrode. IPSCs were blocked by 10 μm bicuculline. Drugs were applied at the times indicated by the horizontal bars. Inset,Representative IPSC traces during control, Win 55,212-2 treatment and bicuculline treatment were superimposed. Each trace is the average of five consecutive sweeps recorded during the indicated treatment.