Fig. 6.

NT-3 deprivation affects retinal development at E14. Sections from control (A) and anti-NT-3-treated embryos (B) were stained with cresyl violet. Retinal ganglion cells are reduced in number, and the inner and outer plexiform layers (thick arrow) are not well structured in treated embryos. In the inner plexiform layer, the double lines (indicated by thin arrows) represent synapses between ganglion cells and neurons from the inner plexiform layer, and they are absent in antibody-treated animals. PE, Pigmented epithelium; GCL, ganglion cell layer.