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Huntingtin expression in human control and HD brain. A, Western blot of 19-week fetal human control brain probed with Ab1 shows expression in all brain regions. For identification of regions, see legend to Figure 1. B, Brain of 10-week-old infant genotyped for a normal allele of 17 CAG repeats and an expanded HD allele of 39 repeats. Note that normal and mutant huntingtin (arrows) are detected in the cortex and cerebellum of this patient.
