Fig. 7.

Demonstration of the extent of huntingtin labeling in medium-sized striatal neurons of the adult mouse.A, B, The upper and lower focal planes of the same field. Asterisks in A identify the position of labeled neurons seen only in B, and asterisksin B identify the position of labeled neurons seen only inA. Not all cells are identified. Many more neurons are labeled when both planes of section are taken into account. The intensity of staining is also variable. Scale bar (shown inA): 50 μm, also applies to B.