Table 2.
Effect of Cd2+ (500 μm) on mEPSC charge distribution and frequency of occurrence
| Cell number | Mean mEPSC charge (picocoulombs) | Mean interevent interval (msec) | ||
|---|---|---|---|---|
| Control | Cd2+ | Control | Cd2+ | |
| 1 | 74 ± 58 | 62 ± 49 | 503 ± 522 | 426 ± 401 |
| 2 | 107 ± 110 | 128 ± 132 | 2960 ± 3090 | 2974 ± 2806 |
| 3 | 68 ± 46 | 81 ± 68 | 542 ± 509 | 596 ± 625 |
| 4 | 58 ± 34 | 58 ± 32 | 2066 ± 2184 | 2159 ± 2035 |
| 5 | 71 ± 52 | 79 ± 50 | 4593 ± 4991 | 2877 ± 33382_a |
| 6 | NAb | 142 ± 131 | 104 ± 1032_a | |
F2_a
In these recordings, the mEPSC frequency of occurrence actually increased in Cd2+(p < 0.05).
F2_b
In this recording, drift in postsynaptic membrane holding current precluded analysis of change in mEPSC charge distribution with Cd2+ application.