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. 1996 Sep 1;16(17):5382–5392. doi: 10.1523/JNEUROSCI.16-17-05382.1996

Fig. 2.

Fig. 2.

LTD in the aged rat exhibits sensitivity to AP5. For five aged slices, AP5 (thick horizontal bar) was bath-applied during the delivery of prolonged LFS (LFS1). After washout, LFS in drug-free medium (LFS2) was administered, and responses were followed for another 15 min before delivery of HFS. The results indicated that the ability of LFS to elicit LTD in area CA1 of the aged slice was impaired in the presence of AP5 and that significant LTD was attained only in drug-free medium. Bars represent SEM.