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. 1996 Oct 15;16(20):6476–6489. doi: 10.1523/JNEUROSCI.16-20-06476.1996

Fig. 8.

Fig. 8.

L-type VDCC activity is involved in bFGF-stimulated neuritic branching. A, Effect of nicardipine (5 μm) on bFGF-stimulated increase in neuritic branching. bFGF and nicardipine were applied at 2 DIV.n = 12 ∼ 20 for each treatment. **p < 0.01 versus control (Duncan’s multiple-range test). B–D, Representative examples of hippocampal neurons at 4 DIV that received no treatment (B), 10 ng/ml bFGF (C), and 10 ng/ml bFGF + 5 μm nicardipine (D) from 2 DIV. Note the marked increase in fine branches along the neurites of the bFGF-treated neuron (C). Nicardipine prevented formation of these branches. Scale bar, 25 μm.