Fig. 7.

Reduction in dendritic and cell body staining of GIRK2 in the wv SN pars compacta (SNc) and ventral tegmental area (VTA). Comparison of coronal sections of wild-type and wv midbrain stained with antibodies against TH (A, D), N terminus of GIRK2 (B, E), or C terminus of GIRK2 (C, F). There is a dramatic decrease in both cell number and dendritic staining of GIRK2-positive neurons in the SNc andVTA, whereas the number of TH-positive neurons decreases in the SNc but remains about the same in the VTA. Scale bar, 0.1 mm.