Fig. 4.

Locomotor activity after vehicle (saline) andd-amphetamine administration (1 mg/kg, s.c) of sham-operated or ibotenic acid-lesioned groups (mean number of beam interruptions per 10 min ± SEM; n = 8–10 per group). A, Temporal profile of locomotor activity at PD35. B, Temporal profile of locomotor activity at PD56. C, Analysis of total activity scores after d-amphetamine reveals that lesioned rats are significantly more active than sham-operated rats only at PD56. *p < 0.01, significantly different from the sham-operated groups; ⁺p < 0.05, significantly different from PD35 lesioned rats.