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. 1996 Nov 15;16(22):7308–7317. doi: 10.1523/JNEUROSCI.16-22-07308.1996

Fig. 2.

Fig. 2.

Elimination of blink reflex hyperexcitability by a microinjection of bicuculline into the superior colliculus of a urethane-anesthetized rat with a 6-OHDA lesion of the ascending mesotelencephalic dopamine system. A, Each trace is the average of 10 rectified OOemg responses to stimulation of the right cornea (R Cornea). Left traces show the right OOemg (R OOemg), the direct response, and theright traces display the left OOemg (L OOemg), the consensual response, not typically seen in normal rats. The top traces illustrate the direct and consensual response before microinjection of bicuculline (Pre Bicuculline), and the bottom traces show the same responses after microinjection of 0.5 μg of bicuculline into the superior colliculus (Post Bicuculline).B, Pooled data from three anesthetized rats with 6-OHDA lesions showing the corneally evoked OOemg amplitude before (Pre), after (Post), and at least 2 hr after (Rec) microinjections of bicuculline into the superior colliculus ipsilateral to the 6-OHDA lesion. All integrated OOemg data were normalized to the mean preinjection OOemg amplitude for all animals, and error bars are 1 SEM.