Distribution of LAT+ cells in the CNS after IC inoculation of the caudato-putamen. Three Balb/c mice that were stereotactically inoculated into the caudato-putamen with 5 × 105 PFU of strain 1716 were killed at day 45 postinoculation. ISH for LATs revealed the presence of LATs in the olfactory system (A), cortex (B, E), caudato-putamen (C), hippocampus (D, E), and brainstem (F). Scale bar: 320 μm in A–C, F; 800 μm in D, E.