Fig. 5.

The paired-pulse facilitation (PPF) ratio of excitatory postsynaptic currents evoked in neurons recorded with control and adenosine-containing electrode solutions. The baseline magnitude of PPF in control neurons was significantly different (p < 0.05) from that in cells loaded with 5 mm adenosine (A), and this difference was abolished during superfusion with 200 μm theophylline. Individual points represent the mean ± SEM for the control (n = 5) or adenosine-loaded (n = 6) group of cells. B, A pair of EPSCs evoked 50 msec apart in a cell recorded with no adenosine added to the pipette. C, Comparable responses in an adenosine-loaded cell (5 mm adenosine); both are averages of seven evoked responses.