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ω-CgTX GVIA (100 nm) reduced transmission at the Schaffer collateral–CA1 synapse under control conditions (evident as reduction in the EPSP/AP complex). In the presence of 4-AP, it had minimal effect on the EPSP/AP complex and slightly reduced the delayed depolarization. In this and the following figures, the initial depolarizations are shown on an expanded time scale in the insets. The data presented are representative of nine experiments with ω-CgTX GVIA used at 100 nm to 1 μm.
