B. DPSP amplitude, duration, and area
| Amplitude (mV) | Standard ACSF duration (msec) | Area | |
|---|---|---|---|
| Control | 12.6 ± 1.1 (n = 28)2_a | 12.1 ± 0.7 | 149 ± 132_b |
| Mutant | 14.6 ± 0.9 (n = 29) | 13.9 ± 1.1 | 189 ± 13 |
| Mg2+-free ACSF + CNQX | |||
| Control | 11.5 ± 1.3 (n = 21) | 39.0 ± 3.6 | 494 ± 96 |
| Mutant | 11.7 ± 1.3 (n = 21) | 49.4 ± 4.3 | 652 ± 118 |
Mean ± SE. Number for each group is in parentheses.
Difference between means for mutants and controls is statistically significantl (t = −2.11, df = 55,p = 0.0396).