Mean (± SEM) time spent in (A) social interaction or percentage of time on open arms of plus-maze, trials 1 (B) and 2 (C), by rats tested 3 min after injection of aCSF (vehicle), 8-OH-DPAT (200 ng), WAY 100635 (200 ng), and 8-OH DPAT (200 ng) + WAY 100635 (200 ng) into the median raphé nucleus. * p < 0.05 compared with control;+ p < 0.05 compared with DPAT + WAY.