Table 2.

Mean (±SEM) of % of time on open arms, and number of closed arm entries made on trial 1 on the elevated plus-maze

Median raphé	n	% time on open arms	Number of closed arm entries
Vehicle	9	22.8 ± 1.5	10.7 ± 1.1
8-OH-DPAT
100  ng	9	43.0* ± 8.4	10.0 ± 0.9
200  ng	10	47.4** ± 4.7	8.4 ± 1.2

Rats were tested 3 min after administration of vehicle (aCSF), 8-OH-DPAT (50, 100, and 200 ng), or (±)tertatolol (3 μg) to the median raphé nucleus or bilaterally to the dorsal hippocampus.

* p < 0.05; **p < 0.01 compared with vehicle.