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. 1996 May 1;16(9):3112–3122. doi: 10.1523/JNEUROSCI.16-09-03112.1996

Fig. 9.

Fig. 9.

Mean ± SEM number of lever-presses as a function of session for rats given access to microinjections of an NMDA receptor antagonist or vehicle directly into the frontal cortex. The number of lever-presses was increased for rats given response-contingent PCP (A) (interaction: F(10,140) = 3.88; p < 0.0001), MK-801 (B) (main effect of sessions: F(1,14) = 8.28; p < 0.02), or CPP (C) (interaction:F(10,140) = 1.91; p < 0.05) into the frontal cortex. Significant differences in the mean number of infusions between animals that received one of the NMDA receptor antagonists and animals that received vehicle for each daily session are depicted as follows (Tukey’s tests): *p < 0.05, **p < 0.01.