Table 1.
Plasma concentrations of ACTH, corticosterone, AVP, OXT, and lactate in conscious male rats under basal conditions and in response to an emotional stressor
| Hormone | Stressor | Basal concentrations | Concentrations at different times after onset of the stress exposure | ||
|---|---|---|---|---|---|
| 15 min | 45 min | 105 min | |||
| ACTH (pg/ml) | Social defeat (n = 6) | 25.7 ± 2.4 | 415 ± 159* | 351 ± 258* | 106 ± 110 |
| Novel cage (n = 6) | 25.2 ± 2.4 | 164 ± 41.0† | 106 ± 49.6* | 32.9 ± 3.4 | |
| Corticosterone (ng/ml) | Social defeat (n = 5) | 9.4 ± 8.1 | 386 ± 84.0* | 346 ± 134* | 238 ± 102 |
| Novel cage (n = 5) | 4.6 ± 3.7 | 269 ± 56.0† | 197 ± 71.0* | 119 ± 88.2 | |
| AVP (pg/ml) | Social defeat (n = 6) | 5.0 ± 1.6 | 2.6 ± 0.7 | 2.1 ± 0.7 | 2.0 ± 1.0 |
| Novel cage (n = 6) | 3.2 ± 0.6 | 2.6 ± 1.1 | 2.0 ± 0.8 | 2.4 ± 0.6 | |
| OXT (pg/ml) | Social defeat (n = 6) | 11.8 ± 4.3 | 13.6 ± 3.2 | 11.9 ± 2.5 | 14.3 ± 6.3 |
| Novel cage (n = 6) | 7.9 ± 0.9 | 12.3 ± 2.8 | 9.7 ± 2.3 | 8.9 ± 2.3 | |
| Lactate (μg/ml) | Social defeat (n = 6) | 56.9 ± 2.2 | 61.7 ± 8.9 | ||
*
p < 0.05,
†
p < 0.01 versus basal.