Fig. 5.

Sequence comparison of regions containing a CaM-binding motif in cone and olfactory CNG channels. Sequence alignment of exon 4-encoded region of ccCNGCα with a homologous region of CNG channels from bovine cone photoreceptor (bcCNGCα; Weyand et al., 1994), rat olfactory epithelium (roCNGCα; Dhallan et al., 1990), and fish olfactory epithelium (foCNGCα; Goulding et al., 1992).Arrowheads indicate the two aromatic or long-chain amino acid residues; + indicates the basic residues; and hrefers to hydrophobic residues in the amphiphilic domain of the CaM-binding site. The stars above the sequences indicate that at least three residues at this position are identical;open circles indicate that at least three residues at this position are conserved.