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D1/D5 dopamine antagonist (+)SCH 23390 decreases early LTP in control slices, whereas inactive enantiomer (−)SCH 23388 is ineffective. Calculation procedures and markings as in Figure 2.A, Summary of seven similar experiments comparing the magnitude of LTP on the same slices in control conditions and after the perfusion of an active enantiomer of the antagonist (+)SCH 23390 (5 μm). B, Inactive enantiomer of D1/D5 dopamine antagonist (−)SCH 23388does not affect early LTP (n = 4).
