Table 3.

Effect of NMDA antagonists on mean relative cell volume at peak veratridine-induced swelling and after long-term veratridine exposure

Experiment	Relative cell volume 15–20 min after veratridine exposure	Relative cell volume 85–90 min after veratridine exposure	Neurons undergoing RVD (%)
100 μm 7-CK	1.78  ± 0.03	1.15  ± 0.06	100
(n = 5;5)		p < 0.0001
5 mm AP-5	1.84  ± 0.18	1.25  ± 0.11	100
(n = 4;5)		p < 0.03
100 μm CNQX (no added glycine)	1.65  ± 0.14	0.95  ± 0.09	100
(n = 5;5)		p < 0.006

Cultures were preincubated with NMDA antagonists for 5 min before the addition of 100 μm veratridine to the bath. Values are mean ± SE.