Table 4.
Correlations between mRNAs, and between mRNA and the learning index, in the rostral dorsal striatum of young (n= 7) and aged (n= 13) Long–Evans rats combined (top), or for aged only (bottom)
Marker | βAPP | b-NOS | GFAP | Mn-SOD | Cu/Zn-SOD |
---|---|---|---|---|---|
Analysis of data for all rats together (young = 7; aged = 13) | |||||
βAPP | 0.84*** | 0.64** | 0.70*** | 0.36 | |
b-NOS | 0.60** | 0.79*** | 0.57** | ||
GFAP | 0.64** | 0.25 | |||
Mn-SOD | 0.66** | ||||
Learning index | 0.59** | 0.52* | 0.56* | 0.64** | 0.43 |
Marker | βAPP | b-NOS | GFAP | Mn-SOD | Cu/Zn-SOD |
---|---|---|---|---|---|
Analysis of data for aged rats only (n = 13) | |||||
βAPP | 0.84** | 0.58* | 0.49 | 0 | |
b-NOS | 0.51 | 0.65* | 0.27 | ||
GFAP | 0.59* | 0 | |||
Mn-SOD | 0.46 | ||||
Learning index | 0.32 | 0.31 | 0.5 | 0.42 | 0.3 |
The film autoradiographs used in Tables 1, 2, and 3 were sampled. For each subject and probe, the dorsal striatum between the rostral end of the globus pallidus and the genu of the corpus callosum was measured (typically 8–10 samples for each subject). Linear regression was used to obtain the r values for correlations between the averaged mRNA levels or between mRNA level and the learning index. Level of significance: *p < 0.05; **p < 0.01; ***p < 0.001.