Fig. 3.

Summary of the region-of-interest densitometric measurements of [³H]-(+)-7-OH-DPAT binding in the dopaminergic (A) terminal regions and (B) cell body fields from Control subjects (n = 9), Cocaine Overdose deaths (n = 6), and Excited Deliriumvictims (n = 6). The density of the D₃receptor was determined in the substantia nigra and throughout the striatum using [³H]-(+)-7-OH-DPAT. The quantitative densitometric measurements demonstrate elevated D₃ receptor densities in the ventral sectors of the striatum, including the nucleus accumbens, and in the lateral and medial sectors of the substantia nigra of the CO deaths. Black bars represent values for drug-free and age-matched controls; stripped bars, CO deaths; stippled bars, ED subgroup. Significant differences from control values, *p < 0.05. Cd, Caudate; ic, internal capsule;Pt, putamen; NA, nucleus accumbens.