Table 2.

Animal behavioral analysis

	Wild type	NR2A−/−	NR2C−/−	NR2A−/−/NR2C−/−
Defecation (count/3 min)	1.68  ± 0.35	1.81  ± 0.34	1.42  ± 0.35	2.04  ± 0.32
Urination (count/3 min)	0.25  ± 0.14	0.44  ± 0.13	0.50  ± 0.15	0.42  ± 0.15
Grip strength	66.4  ± 1.6	66.0  ± 1.7	64.8  ± 1.1	66.0  ± 1.6
Righting reflex (sec)	0.18  ± 0.08	0.19  ± 0.07	0.19  ± 0.08	0.19  ± 0.09

All data are given as mean ± SEM. For analysis of defecation and urination, an animal was placed in a novel environment of the open-field, and the frequency of defecation and urination was measured during the first 3 min. The grip strength and the time required for righting reflex were measured according to the procedures described in Materials and Methods. The numbers of animals tested were 16–24 for the analyses of defecation and urination and 5 for the analyses of grip strength and righting reflex. No statistically significant difference was noted for any of the animal behaviors analyzed.