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Effect of picrotoxin on paired-pulse inhibition and facilitation in the LPP and MPP
| 20 msec IPI | 80 msec IPI | |||
|---|---|---|---|---|
| CON | PTX | CON | PTX | |
| MPP | −22.5 ± 2.4 | −12.7 ± 4.3 | −9.42 ± 6.4 | 0.48 ± 3.3 |
| LPP | 9.76 ± 5.1 | 5.53 ± 6.6 | 32.1 ± 3.1 | 16.7 ± 2.81-a |
Percentage change ± SEM in fEPSP amplitude relative to conditioning pulse.
Significant difference from control group (t test independent samples, p < 0.01.)
Control, n = 8; picrotoxin (PTX), n = 9. IPI, Interpulse interval.
