Table 4.

Comparison of effects on neuronal survival of NGF exposure during and after hypoglycemic stress

Treatment during stress	Neurotrophin after stress	Neuronal survival (%)
None	None	14.8  ± 4.72  (9)
None	NGF	28.6  ± 3.84  (6)
NGF	None	60.5  ± 5.12  (13)*
NGF	NGF	65.5  ± 6.45  (9)*

Hypoglycemic stress protocol as described in Materials and Methods. Total neuronal survival expressed as a percentage (mean ± SEM) of the Alamar Blue reduction measured in nonstressed sister cultures. Number of culture wells for each treatment is indicated in parentheses. *, Significant difference from survival measured in cultures with no exogenous neurotrophin during the stress (p < 0.01, Dunnett’s test).