Fig. 10.
The functional capacity of the intraterminal ryanodine-sensitive store as assayed by caffeine facilitation of intraterminal Ca2+ release. A, The trace was the change in resting [Ca2+]i(Δ[Ca2+]r) induced by bath application of 10 mm caffeine. The heavy bar below the trace marks the duration of caffeine presence. The resting [Ca2+]i returned to its control level in 5 min. B, The rate of increase of terminal [Ca2+]r in response to 10 mmcaffeine. Time 0 indicates the beginning of the caffeine-induced rise of the resting [Ca2+]i.