Fig. 3.
Effect of ryanodine on Δ[Ca2+]i in the presynaptic terminals synapsing onto a C cell. A–C, Superimposed traces are Δ[Ca2+]i recorded in normal Ringer solution and in ryanodine (RY) evoked by 200 (A), 400 (B), and 800 (C) stimuli. Ryanodine (10 μm) was added to the bathing solution after the effects of 1 μm RY on different responses were recorded. For each panel, the dotted vertical lines correspond to the beginning and the end of 20 Hz stimulation, and the thin line at thebottom indicates the 0 [Ca2+]ilevel.