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. 1996 Aug 15;16(16):4881–4889. doi: 10.1523/JNEUROSCI.16-16-04881.1996

Fig. 6.

Fig. 6.

Effects of intracellularly applied salicylate on OHC capacitance and movement. Voltage-dependent capacitance and voltage-induced length change were measured 3–4 min after whole-cell configuration in three different cells. As the concentration of salicylate increased, voltage-dependent capacitance and nonlinearity of voltage-induced length change were reduced correspondingly. Length changes were induced by 20 mV steps from −150 to +150 mV at aVhold of −80 mV.Rs, 3.38 MΩ andRm, 66.5 MΩ (closedcircles); Rs, 3.68 MΩ andRm, 34.7 MΩ (opencircles); Rs, 6.57 MΩ andRm, 240 MΩ (opentriangles). Fits (solid lines) for capacitance indicate VpkCm,Qmax, and z of −14.3 mV, 4.74 pC, and 0.650 (open circles); −38.2 mV, 5.09 pC, and 0.317 (closed circles); −28.7 mV, 36.54 pC, and 0.111 (open triangles). Fits for the mechanical data indicate Vhold and z of −36.4 mV and 0.955 (closed circles), 2.89 mV and 0.376 (open circles), and 6.43 mV and 0.039 (opentriangles). The inset shows the first derivative of the mechanical responses, indicating the gain of the mechanical response with different concentrations of salicylate. See text for details.