Skip to main content
. 1996 Aug 15;16(16):5141–5153. doi: 10.1523/JNEUROSCI.16-16-05141.1996

Fig. 3.

Fig. 3.

Effects of substance P on large aspiny neurons.A, Substance P evoked depolarization in the current-clamp mode (a) and elicited an inward current in the voltage-clamp mode (−60 mV) (b). TTX (0.3 μm) was also applied in b. Note that membrane conductance increased after application of SP. Depolarizing and hyperpolarizing voltage pulses (±10 mV, 100 msec) were applied before and during SP application. B, Pretreatment with an SP antagonist suppressed the SP-induced inward current in a dose-dependent manner. The recordings in a and b are for the same cell.