Table 1.
Structural complexes of TAR in complex with small molecules
| TAR type | Ligand | Ligand scaffold | Method | PBD codes | Refs. |
|---|---|---|---|---|---|
| HIV-1 | Arginine | Amino acid | NMR | 1arj | 103 |
| HIV-2 | Argininamide | Amino acid derivative | NMR | 1akx and 1aju | 69 |
| HIV-1 (Δ apical loop) | Calcium ion | Divalent ion | X-ray | 397d | 112 |
| HIV-1 | Neomycin | Aminoglycoside | NMR | 1qd3 | 92 |
| HIV-1 | Acetylpromazine | Phenothiazine drug | NMR | 1lvj | 109 |
| HIV-1 | RBT-550 | Benzyl indole | NMR | 1uts | 106 |
| HIV-1 | RBT-203 | Methoxy phenoxy | NMR | 1uud | 107 |
| HIV-1 | RBT-158 | Benzylpiperazine | NMR | 1uui | 107 |
| HIV-1 | Chemical probe | 4-Methoxynaphthalene-2-amine | NMR | 2l8h | 95 |