Table 3. Physical properties of the wild type, carbonylated and carbonylated_HP NPCs.

In the carbonylated_HP NPC only the effect of carbonylation on the hydrophobicity is accounted for. For the net hydrophobicity, we added the hydrophobicity values ε of all the residues inside the NPC.

Force field	+ve Charged AA	-ve Charged AA	Net charge	Net hydrophobicity
Wild type	8072	7560	+512	43373.7
Carbonylated	0	7560	−7560	45549.7
Carbonylated_HP	8072	7560	+512	45549.7