KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Chemicals, Peptides, and Recombinant Proteins
Human FGF21	Eli Lilly and Company, Indianapolis, IN	N/A
Critical Commercial Assays
FGF21 ELISA	Biovendor	RD291108200R
Insulin ELISA	EMD Millipore	EZRMI-13K
Adiponectin ELISA	EMD Millipore	EZMADP-60K
Experimental Models: Organisms/Strains
Mouse:FGF21-KO	Dr. Steven Kliewer	Potthoff et al., 2009
Mouse: Camk2a-Cre	Dr. Steven Kliewer	Casanova et al., 2001; Bookout et al., 2013
Mouse: Adiponectin-Cre: B6.FVB-Tg(Adipoq-cre)1 Evdr/J	The Jackson Laboratory	Stock No: 028020
Mouse: Klblox/lox (Klbtm1)	Dr. Steven Kliewer	MGI:5446168 Ding et al., 2012
Oligonucleotides
Fgf21 Forward: CAAATCCTGGGTGTCAAAGC;	Integrated DNA Technologies (IDT)	N/A
Fgf21 Reverse: CATGGGCTTCAGACTGGTAC	IDT	N/A
Klb Forward: CAGGGATATCTACATCACAGCC	IDT	N/A
Klb Reverse: GTAGCCTTTGATTTTGACCTTGTC	IDT	N/A
Fas Forward: GGGATCTGGTGAAAGCTGTAG	IDT	N/A
Fas Reverse: GTGTTCTCGTTCCAGGATCTG	IDT	N/A
Scd-1 Forward: CTGTACGGGATCATACTGGTTC;	IDT	N/A
Scd-1 Reverse: CGTGCCTTGTAAGTTCTGTG	IDT	N/A
Srebp1 Forward: AGATTGTGGAGCTCAAAGACC	IDT	N/A
Srebp1 Reverse: CACl 1CGTAGGGTCAGG1 1C	IDT	N/A
Ucp1 Forward: CACCTTCCCGCTGGACAC	IDT	N/A
Ucp1 Reverse: CCCTAGGACACCTTTATACCTAATGG	IDT	N/A