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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Mov Disord. 2019 Apr 7;34(6):866–875. doi: 10.1002/mds.27659

Figure2: SNCA association with Parkinson’s disease age at onset.

Figure2:

A) Locus zoom plot of the association signal of the SNCA locus. The age at onset association signal is primarily based at the 3’ end of the SNCA gene, highly similar as the Parkinson’s disease GWAS signal of Chang et al 2017 (Supplementary Figure8). B) Conditional analysis based on the most associated SNP (rs356203) shows that there is a secondary signal at the 5’ end of the SNCA gene rs6532192, as well similar as previously reported for the Parkinson’s disease GWAS Chang et al 2017.