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. Author manuscript; available in PMC: 2020 Jun 10.
Published in final edited form as: J Control Release. 2019 Apr 9;303:1–11. doi: 10.1016/j.jconrel.2019.04.010

Table 1.

Physicochemical properties of DNA-NP.

Hydrodynamic diameter ± SEM (nm)a PDIa ζ-Potential ± SEM (mV)b Hydrodynamic diameter ± SEM at 12 hours in aCSF (nm)c PDI at 12 hours in aCSFc
CPN 50 ± 1 0.16 18.0 ± 0.2 212 ± 3 0.17
BPNL 49 ± 1 0.19 7.0 ± 0.3 67 ± 6 0.16
BPNH 48 ± 5 0.20 2.0 ± 0.1 56 ± 3 0.15

a Hydrodynamic diameter and polydispersity index (PDI) were measured by dynamic light scattering (DLS) in 10 mM NaCl. Mean ± SEM (n ≥ 3).

b ζ-potential was measured by laser Doppler anemometry in 10mM NaCl at pH 7.0. Mean ± SEM (n ≥ 3).

c Hydrodynamic diameter and PDI were measured by DLS following a 12-hour incubation in aCSF at 37° C.