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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Crit Care Med. 2019 Jul;47(7):951–959. doi: 10.1097/CCM.0000000000003779

Figure #3:

Figure #3:

Amount of resuscitative IV fluid administered in select sepsis trials and 60-day mortality.

The area of the circle is proportional to trial sample size. Resuscitative fluid volume in ml/kg for Rivers, ProMISe and ProCESS are estimated based upon an average 80kg participant. ProMISe and ARISE study groups combined into single circle secondary to significant overlap in IV fluid administered and mortality between study groups. EGTD = early goal directed therapy, P = protocol, R = restricted, UC = usual care.