Table 2.
Combined Grade 3+ Toxicities By Age From E2297 And E6201
| Toxicity Rates (%) |
|||
|---|---|---|---|
| Toxicity Type | ≥ 75 Years | <75 Years | P-Value |
| Fatigue* | 29.7 | 16.8 | 0.004 |
| Neutropenia | 27.7 | 21.6 | 0.11 |
| Thrombocytopenia | 25.0 | 17.1 | 0.03 |
| Infection | 9.5 | 4.8 | 0.03 |
| Anemia | 8.8 | 11.3 | 0.48 |
E2297 Had 321 Cases (Out Of 322) Assessable For Toxicity; E6201 Had 802 Cases (Out Of 824) Assessable For Toxicity. 14% Of Total Study Population (N=157) Was ≥75 Years Old.
Fatigue Only Assessed In E6201