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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: J Geriatr Oncol. 2018 Dec 18;10(4):540–546. doi: 10.1016/j.jgo.2018.11.001

Table 2.

Combined Grade 3+ Toxicities By Age From E2297 And E6201

Toxicity Rates (%)
Toxicity Type ≥ 75 Years <75 Years P-Value

Fatigue* 29.7 16.8 0.004
Neutropenia 27.7 21.6  0.11
Thrombocytopenia 25.0 17.1  0.03
Infection   9.5   4.8  0.03
Anemia   8.8 11.3  0.48

E2297 Had 321 Cases (Out Of 322) Assessable For Toxicity; E6201 Had 802 Cases (Out Of 824) Assessable For Toxicity. 14% Of Total Study Population (N=157) Was ≥75 Years Old.

*

Fatigue Only Assessed In E6201