A, Representative 13C MR spectra recorded at 7 T in subcutaneous EL4 and LL2 tumors, normal brain, heart and liver, and kidneys 15 s after injection of hyperpolarized [U-13C6, U-2H7]-D-glucose (350 μL, 100 mM) into a tumor bearing mouse. B, Representative 13C chemical shift images recorded 15 s after i.v. injection of hyperpolarized [U-13C6, U-2H7]-D-glucose (400 μL, 200 mM) into an EL4 tumor bearing mouse. The location of the tumor is marked in white in the 1H MR image. (Reproduced with permission from Reference 63)