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. 2019 Jun 11;7:135. doi: 10.3389/fbioe.2019.00135

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Copyright © 2019 Mobaraki, Abbasi, Omidian Vandchali, Ghaffari, Moztarzadeh and Mozafari.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mechanical injury was induced in murine corneas by scraping the epithelium and either topical recombinant hepatocyte growth factor (HGF) was applied twice daily. Normal corneas without injury or injured corneas receiving MSA served as controls. Corneas were harvested at day 3 after injury. (A) Representative immunofluorescent images of sections of mouse cornea stained for Ki-67 (green) showing proliferating cells (scale bar, 100 mm). (B) Representative immunofluorescence images of corneal cross sections showing higher expression of CD45 (green) in MSA-treated controls, compared to HGF-treated eyes (scale bar, 50 mm). Reprinted with permission from Omoto et al. (2017).