Table 2.
Influences of prenatal stress and the drugs on behavior in the forced swim test, hot plate test and formalin test.
| Stress/No Stress | Groups | Forced swim test | Hot plate test | Formalin test | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Flexing + Shaking | Licking duration | ||||||||||||||||
| First phase | Interphase | Second phase | First phase | Interphase | Second phase | ||||||||||||
| No Stress | V-PNS | ¬♂ | ¬♀ | ¬♂ | ¬♀ | ¬♂ | ¬♀ | ¬♂ | ¬♀ | ¬♂ | ¬♀ | ¬♂ | ¬♀ | ¬♂ | ¬♀ | ¬♂ | ¬♀ |
| ♂ n = 9 | |||||||||||||||||
| ♀ n = 9 | |||||||||||||||||
| Stress | V-PS | ♂*** | ♀*** | ♂* | ♀* | ♂** | ¬♀ | ♂* | ¬♀ | ♂*** | ¬♀ | ¬♂ | ♀* | ¬♂ | ♀* | ♂*** | ♀* |
| ♂n = 12 | |||||||||||||||||
| ♀ n = 11 | |||||||||||||||||
| F-PS | ♂*** | ♀*** | ¬♂ | ¬♀ | ♂+ | ¬♀ | ¬♂ | ¬♀ | ♂+ | ¬♀ | ¬♂ | ¬♀ | ¬♂ | ¬♀ | ♂+++ | ♀+ | |
| ♂n = 14 | |||||||||||||||||
| ♀ n = 12 | |||||||||||||||||
| B-PS | ♂*** | ♀*** | ♂** | ♀** | ♂∧∧ | ¬♀ | ♂∧∧∧ | ¬♀ | ♂∧∧ | ¬♀ | ♂∧ | ♀∧∧ | ¬♂ | ♀∧ | ♂∧∧∧ | ♀∧∧∧ | |
| ♂n = 11 | |||||||||||||||||
| ♀ n = 9 | |||||||||||||||||
| FB-PS | ♂*** | ♀*** | ♂*** | ♀*** | ♂### | ¬♀ | ♂# | ¬♀ | ♂## | ¬♀ | ¬♂ | ♀## | ¬♂ | ¬♀ | ♂### | ♀### | |
| ♂n = 21 | |||||||||||||||||
| ♀ n = 14 | |||||||||||||||||
Note: the symbols define effects in females and males. The “¬” before the symbol means that there was no significant effect for that behavior for that sex. *, **, *** mean the effect of V-PS as compared to V-PNS; +, +++; ∧, ∧∧, ∧∧∧; #, ##, ### mean the effect of F-PS, B-PS, FB-PS, respectively, as compared to V-PS. V-PNS, vehicle, prenatally non-stressed; V-PS, vehicle, prenatal stress; F-PS, fluoxetine, prenatal stress; B-PS, buspirone, prenatal stress; FB-PS, fluoxetine, buspirone and prenatal stress. The data in the table have been analyzed separately for all indicators.