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Modulation of systemic cytokine production in chronic chagasic mice treated with BA5 or benznidazole. Effects of BA5 (10 or 1 mg/Kg) or benznidazole (Bdz; 100 mg/Kg) in serum concentrations of TNF-α (A), IFN-γ (B), IL-1β (C) and IL-10 (D). Values represent the means ± S.E.M. of 5 mice (naïve) or 10 mice (infected) per group. *P< 0.05 compared to vehicle-treated mice; #P < 0.05 compared to naive group. $P < 0.05 compared to benznidazole-treated group.
